Aggressive fluid therapy in Acute Pancreatitis is harmful

Enrique de-Madaria, M.D., Ph.D., James L. Buxbaum, M.D., Patrick Maisonneuve, Dipl.Eng., Ana García García de Paredes, M.D et el published study in NEJM comparing aggressive versus moderate fluid therapy in Acute pancreatitis.  BACKGROUND Early aggressive hydration is widely recommended for the management of acute pancreatitis.  This is based on animal model observation of regional hypoperfusion … Read more

Restrictive versus Liberal fluids in Septic shock

Tine S. Meyhoff, Peter B. Hjortrup et el(Classic Trial Group-Conservative versus Liberal Approach to Fluid Therapy of Septic Shock in Intensive Care) published study in NEJM comparing restrictive vs standard fluid therapy in septic shock. WHAT This was an international, stratified, parallel-group, open-label, randomized clinical trial in 31 ICUs in Denmark, Norway, Sweden, Switzerland, Italy, … Read more

Difficult airway algorithm

The American Society of Anesthesiologists (ASA) released their much anticipated difficult airway guidelines.  The new guidelines emphasize following-  Oxygenation prior to and throughout attempts at airway management. Use of end tidal CO2 after each attempt at airway management, regardless of the airway device or technique used. The role of clinical measures (eg, chest rise and fall, … Read more

Pantoprazole reduces GI bleeding in intubated patients without improving mortality.Read more