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Brief News

4/1/2025

Severe Sepsis and Septic Shock Management Bundle (SEP-1) implementation does not work.

2/20/2025 Inhaled sedation with Sevoflurane associated with worse outcome in ARDS. 1/12/2025 Thymosin α1 not effective in sepsis. 12/12/2024 No difference in outcomes with IV or IO in out of hospital cardiac arrest. 10/2/2024 Liberal blood transfusion may improve neurological outcome in acute brain injury patients. 9/25/2024 Early mechanical ventilation(Day 1) in sepsis may improve outcome. 9/10/2024 Risk of atrial fibrillation after CABG same for low(3.6) vs high(4.5) potassium level. 9/1/2024 Intubation during transport leads to hemodynamic collapse. 8/20/2024 Moderate IV Fluid Resuscitation (4 litres) Is Associated With Decreased Sepsis Mortality. 7/15/2024 Pantoprazole reduces GI bleeding in intubated patients without improving mortality. 6/15/2024 Intravenous Amino Acids prevent kidney injury in cardiac surgery patients. 6/11/2024 Noninvasive Ventilation before intubation prevents hypoxia in emergent intubation. 5/19/2024 Video laryngoscopy better, in operating room as well. 4/19/2024 Hydrocortisone plus fludrocortisone improve mortality in CAP with Septic Shock. 3/20/2024 No difference in mortality between high(PaO2 90) vs low(PaO2 60) in intubated Covid patients. 3/1/2024 Probabilities of survival rapidly declines over time during CPR, less than 1% at 39 minutes. 2/1/2024 Haloperidol improves mortality in patients with delirium admitted to ICU. 1/2/2024 Etomidate use for endotracheal intubation in critically ill patients increases mortality. 12/23/2023 Daily toothbrushing reduces pneumonia and improves mortality in ICU. 12/11/2023 Prophylactic Minocycline may reduce ICU delirium. 12/3/2023 Prone positioning during ECMO for ARDS does not help. 11/26/2023 Small-Volume Blood Collection Tubes Reduce Transfusions in Intensive Care. 11/19/2023 Resuscitative endovascular balloon occlusion of the aorta (REBOA) does not improve mortality in trauma patients with exsanguinating hemorrhage. 11/18/2023 Early and empirical high-dose cryoprecipitate in trauma does not improve survival. 11/01/2023 Inhaled Amikacin reduces the incidence of Ventilator-Associated Pneumonia. 10/24/2023 Convalescent Plasma reduces mortality by 10% in Covid-19 on Mechanically Ventilation. 10/21/2023 Hydrocortisone outperforms(mortality benefit) all other steroids for community acquired pneumonia. 10/15/2023 No difference between Cefepime and Pip-Tazo in terms of acute kidney injury, need for renal replacement therapy, or death in sepsis. 10/14/2023 Betablockers harmful in septic shock treated with norepinephrine. 10/1/2023 PEEP of 10 ideal for ARDS patients on VV ECMO. 9/19/2023 Propafanone as good as Amiodarone for AFib in septic shock. 9/1/2023 Obese patients who need ECMO have better outcome than patients with normal BMI. 8/20/2023 Surgical rib fixation does not improve QOL in severe chest injury. 7/2/2023 Procalcitonin at admission not reliable for capturing bacteremia in sepsis. 6/28/2023 Catheter-directed thrombolysis compared with systemic thrombolysis and anticoagulation improves survival in in patients with intermediate- or high-risk pulmonary embolism. 6/12/2023 Continuous infusion of meropenem does not improve outcome in sepsis. 6/5/2023 Prehospital administration of tranexamic acid in severe trauma does not improve outcome. 6/1/2023 No difference between anakinra plus standard care vs standard care alone for reducing mortality risk or need for mechanical ventilation among patients hospitalized with severe COVID-19 pneumonia and hyperinflammation. 5/20/2023 Mannitol and Hypertonic Saline equally effective in TBI. 5/17/2023 No difference between higher dose methylprednisone and standard dexamethasone in COVID 19. 5/15/2023 Secondary bacterial pneumonia, not cytokine storm caused deaths in COVID 19. 4/12/2023 BCG vaccination doesn't prevent COVID. 3/31/2023 High dose DVT prophylaxis better than standard dose in COVID hypoxic respiratory failure. 3/20/2023 Fludrocortisone added to hydrocortisone was associated with increased hospital survival, shorter length of stay, and decreased shock duration in septic shock. 2/28/2023 Condom catheters can be deadly.

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